Melanomas that occur in mucosal locations are lumped into this category (vagina, esophagus, etc).
ACRAL LENTIGINOUS MELANOMA: a rare variety (1% of melanomas) arising on the volar aspects of feet (92%) and hands (8%). NODULAR MELANOMA: by definition an invasive tumor (very little radial growth). Radial growth pattern before and during vertical phase (therefore these tumors, like lentigo maligna, can get rather large, but still are usually less than 3 cm in diameter).ģ. SUPERFICIAL SPREADING MELANOMA: Confluent atypical cell nests at junction prominent May get large, up to 6 cm in greatest diameter. LENTIGO MALIGNA MELANOMA: usually on face. exception is nodular melanoma (which has virtually no radial phase).ġ.
Radial spread (laterally) usually occurs first, before the lesion Perhaps with recent change enlargement, irritation, ulceration or bleeding.Į. S/S: a "mole" with irregular borders and/or "blotchy" coloration in shades of red, white, blue, and black, Melanoma can also occur in deep soft tissues (clear cell sarcoma, melanoma of soft parts), in the retina (eye grounds appear black, no "red reflex"), esophagus and ano-rectal region.ĭ.
#DARKEN LAYER IN KEYLIGHT 1.2 SKIN#
skin usually, generally in sun-exposed regions.(Note: normal number of nevi is approximately 20, total body) "WASPs" are at greater risk than non-WASPS (White, Affluent people who are Sun sensitive and/or have Precursor moles).A predisposition for development of melanoma may be inherited through DNS (dysplastic nevus syndrome). Women have better tumor survival rates than men. malignancy of melanocytes most common in light skinned populations, especially those with increased sun exposure.